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books أنواع كودون البدء

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أنواع كودون البدء (Info)


في حقيقيات النوى يكون كودون البدء في العادة الكودون AUG ... ولكن الكودون AUG لا يعمل فقط ككودون بدء فقط وإنما يشفر أيضا لإنتاج الحمض الأميني ميثيونين .

وفي بدائيات النوى يمكن أن تستخدم كودونات بدء أخرى إلى جانب AUG ؛ مثل GUG و UUG لتشفير أول فورميلميثيونين . فمثلا تستخدم الإشريكية القولونية الكودون AUG (بنسبة 77 %) و GUG [بنسبة 14 %) و UUG (بنسبة 8 %) وبعض كودونات أخرى أقل استخداما . من الأمثلة المعروفة لجينات لا تستخدم AUG ككودون بدء نجد (GUG) لإنتاج lacI و (UUG) لإنتاج lacA في مشغل اللكتوز للإشريكية القولونية .

Source: wikipedia.org
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