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ريبوزيم رأس المطرقة (Info)


ريبوزيم رأس المطرقة (بالإنجليزية: Hammerhead ribozyme)‏ هو نمط رنا (تسلسل محدد) يقوم بتحفيز تفاعلات قص ووصل قابلة للعكس في موقع محدد من جزيء رنا، وهو واحد من عدة جزيئات رنا محفِّزة (ريبوزيمات) متواجدة طبيعيا. يُستخدم ريبوزيم رأس المطرقة كنظام نموذجي للبحث عن بنية وخصائص الرنا ويُستعمل في تجارب قص الرنا المستهدفة، والتي لبعضها تطبيقات علاجية مقترحة. سُمي برأس المطرقة لتشابه مخططات بنيته الثانوية الأولى بالقرش المطرقة. اكتُشفت ريبوزيمات رأس المطرقة في البداية في قسمين من جزيئات الرنا التي تشبه فيروسات النبات: الرنا التابع والفيرويد، ثم تم العثور عليها لاحقا منتشرة بكثرة لدى مختلف أشكال الحياة.

أُبلغ عن تفاعلات القص الذاتية أول مرة سنة 1986 كجزء من آلية التضاعف الدائري الملتف (en). تسلسل ريبوزيم رأس المطرقة كفيل لإحداث القص الذاتي ويعمل عبر تشكيل بنية محفوظة ثلاثية الأبعاد.

Source: wikipedia.org
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Novels And Literary Stories Islamic Religion Human Development And Self-development History Islamic Fiqh Literature Interpretation Of The Koran Philosophy And Logic Islamic Faith The Culture Biographies, Translations And Life Of The Famous People Biography Of The Prophet Muhammad, May God Bless Him And Grant Him Peace Psychology Teaching English English Islamic Philosophy Arabic Literature Arabic Sciences Of The Noble Qur’an And The Sunnah Of The Prophet Political Science And Strategy History Acclamation The Holy Qur'an Engineering Poetry And Poets Education More of Book Categories

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