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Platelet-rich fibrin (PRF) substance is a by-product of blood (plasma) that is rich in platelets. PRF, in short, is simply a byproduct of blood. It is exceptionally high in platelets and growth factors, the “signaling” molecules that allow communication between cells. PRF is a tool that significantly improves bone and soft tissue regeneration. Recently, its use has been advocated for regenerative periodontics and wound healing.
Platelet-rich fibrin is the new thing when it comes to surgery, with improved healing and immune support. The operation can have a faster and better recovery, with fewer post-operative complications. The application of platelet-rich fibrin during the implantation process enhanced the stability of the implants. The application of platelet-rich fibrin improves the stability of the implant in the first week of osseointegration. The biggest advantage of using platelet-rich fibrin is its complete absorption, thus avoiding the time of the second surgery, which is definitely a critical factor in elderly patients. This appears to be a minimally invasive technique with low risk and satisfactory clinical outcomes such as preventing complications or implant failure especially in age-related elderly patients.