كتب odonogenesis

In human,20 primary and 32 permanent teeth develop from the interaction of oral epithelial cells and underlying mesenchymal cells. Each developing tooth grows as an anatomically distinct unit, but the basic developmental process is similar for all teeth.
Odontogenesis is a highly co-ordinated and complex process which relies upon cell to cell interaction that results in the initiation and generation of the tooth. The gross histological processes are well documented, the mechanisms that are involved at a molecular level are only now beginning to be elucidated due to the revolution in molecular biological techniques that has occurred over the last decade. During their early development, tooth germs exhibit many morphological and molecular similarities with other developing epithelial appendages, such as hair follicles, mammary and salivary glands, lungs, kidneys, etc. The developing tooth germ, which is an experimentally accessible model for organogenesis, provides a powerful tool for elucidating the molecular mechanisms that control the development of these organs. There have been tremendous advances in recent years towards a better understanding of the regulation of tooth development.